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肌钙蛋白Ⅰ与肌红蛋白定时定量监测在急性心肌梗死诊疗过程中的临床观察

Clinical Observation of Quantitative Analysis of Cardiac Troponin I and Myoglobin in Patients with Acute Myocardial Infraction

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【作者】 胡章学张涛王婷孟红

【Author】 HU Zhang-xue ZHANG Tao WANG Ting (Department of Nuclear Medicine,Ankang Central Hospital,Ankang 725000,China)

【机构】 安康市中心医院核医学科安康市中心医院核医学科 陕西安康725000陕西安康725000

【摘要】 根据心肌肌钙蛋白Ⅰ(cTnI)与肌红蛋白(Mb)在急性心肌梗死(AMI)发生后的定时定量分析结果比较,为AMI的早期诊断提供更灵敏、更准确的监测指标。本文采集95例AMI患者于胸痛发作0~4h、8h、12h、24h、48h、3天、5天和7天的血清,以及对照组38名的空腹血清同步进行cTnI与Mb的动态检测和比较,结果发现,AMI患者的早期0~4h Mb的灵敏度明显高于cTnI;而8h后cTnI的灵敏度和准确度明显高于Mb。

【Abstract】 To explore the clinical value of cardiac troponinⅠ(cTnⅠ)and myoglobine(Mb)in the early diagnosis of acute myocardial infraction(AMI),the serum cTn I and Mb were detected in 95 AMI patients at various time phase including 0~4 h,8 h,12 h,24 h,48 h,3 days,5 days and 7 days after they got breast-ach,and 38 healthy controls.The results showed that the sen- sitivity of Mb in the diagnosis of AMI was higher than that of cTnI when the AMI occurred in 0~4 hours.However,the sensitivity and accuracy of cTnI in the diagnosis of AMI were higher than that of Mb in 8 hours later.

  • 【文献出处】 标记免疫分析与临床 ,Labeled Immunoassays and Clinical Medicine , 编辑部邮箱 ,2007年04期
  • 【分类号】R542.22
  • 【被引频次】10
  • 【下载频次】104
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