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双波长分光光度法测定复方地氯霜中氯霉素的含量
Determination of chloramphenicol in dexamethasone and chloramphenicol compound cream by dual-wavelength spectrophotometry
【摘要】 目的建立复方地氯霜中氯霉素的含量测定方法。方法采用双波长分光光度法测定氯霉素的含量。选择测定波长为268 nm,参比波长为248 nm。结果氯霉素的平均回收率为104.3%,RSD为2.93%(n=6)。结论该方法简便、准确,适用于该制剂的质量控制。
【Abstract】 Aim To establish a method for the determination of chloramphenicol in dexamethasone and chloramphenicol compound cream.Methods A dual-wavelength spectrophotometry was used.The selected determining wavelength was 268 nm and the reference wavelength was 248 nm.Results The average recovery of chloramphenicol was 104.3%,and RSD was 2.93%(n=6).Conclusion This method is simple,accurate and suitable for assay of the preparation.
- 【文献出处】 安徽医药 ,Anhui Medical and Pharmaceutical Journal , 编辑部邮箱 ,2007年12期
- 【分类号】R927
- 【被引频次】2
- 【下载频次】47