【摘要】 背景与目的:探讨不同强度低功率微波辐射对雄性小鼠生殖系统的影响。材料与方法:48只雄性ICR小鼠,随机分为3个辐射组和1个对照组,每组各12只,辐射组用频率900MHz,功率密度分别为250、150、50μW/cm2的连续波,对小鼠每天辐射24h,连续辐射34.5d。辐射结束观察小鼠性行为能力的扑捉潜伏期(capture incubation period,CIP)、睾体比、睾丸病理变化、精子相对计数、精子畸形率及血清睾酮等指标的变化。结果:各辐射组与对照组比较,150μW/cm2组小鼠CIP明显延长(P<0.05)、睾丸发生轻微病理变化、精子相对计数明显减少(P<0.05);精子畸形率明显增加(P<0.05);血清睾酮水平明显降低(P<0.05);睾体比之间的差异无统计学意义。结论:低功率微波辐射(150μW/cm2)能引起雄性小鼠睾丸病理改变,性功能(CIP)减退,精子相对计数减少,精子畸形率升高,血清睾酮水平降低,影响雄性小鼠生殖功能。更多还原

【Abstract】 BACKGROUND & AIM:To explore the effects of different intensities of low power microwave on the male reproductive system in mice.MATERIALS AND METHODS:48 adult male mice were randomized into 3 microwave groups and 1 control group,each with 12 animals:microwave groups was exposed to 900 MHz microwave(250 μW/cm2,150 μW/cm2,50 μW/cm2,24 h/d for 34.5 d) and control group was not exposed to microwave.The sexual function:capture incubation period(CIP),the pathomorphological changes of the testes,testis-weight ratio,comparative sperm count,malformed sperm ratio and serum testosterone were used to assess the effects of the low power microwave.RESULTS:In microwave group exposure(150 μW/cm2)testis showed slight pathological changes,comparative sperm count,serum testosterone level were significantly decreased compared with the normal control(P<0.05,respectively).CIP,sperm malformed ratio in microwave group were significantly increased compared with the normal control group(P<0.05,respectively).But testis-weight ratio showed no significant difference compared with the control(P>0.05,respectively).CONCLUSION:Low power microwave exposure(150 μW/cm2)could weaken sexual function(CIP) and induce pathological changes of testis,obvious increase of sperm malformed ratio,significant decrease of comparative sperm count and serum testosterone in mice.更多还原