【摘要】 目的探讨原发性鼻腔鼻安恶性黑色素瘤的诊断和治疗效果。方法对本院1991～2004年收住的20例鼻腔鼻窦原发性恶性黑色素瘤的临床资料进行回顾性分析。结果所有患者均得到手术治疗技术后放疗。1年,3年和5年生存率分别为75.0%,38.9%和20.0%。生存期最短15个月,最长达11年以上。结论本病发展快,预后差,临床早期诊断及时治疗甚为重要。治疗主张采用综合疗法,即广泛彻底切除肿瘤并辅以放疗。对于单纯的局部复发可以进行多次的扩大切除。更多还原

【Abstract】 To explore the diagnosis and treatment of primary malignant melanoma in nasal cavily and paranasal sinuses.Methods Twenty cases of melanoma treated in our department from 1991 to 2004 were analysed retrospectively.Results All patients underwent surgical resection and received postoperative radiotherapy.The 1-year,3- year and 5-year survival rate in all were 75.0%,38.9% and 20.0%.The shortest survival period was 15 months,the longest over 11 years.Conclusion Primary malignant melanoma in nasal cavity and paranasal sinuses was characterized rapid development and poor prognosis,early diagnosis and adequate resection are important.Combined treatment(operation and radiation)should be adopted.The cause of failure in the treatment was local uncontrol or recurrence.In this case,it was treated with surgery again,even more times.更多还原