【摘要】 目的探讨焦虑症（AD）和抑郁症的关联性负变（CNV）变异。方法应用 Nicolet Bravo 脑诱发电位仪,采用光和声成对刺激以及反应时间技术,记录了37例 AD 患者的 CNV,并与36例健康成人（NC）和32例抑郁症患者的 CNV 进行比较。结果AD 和抑郁症组波形不规则,CNV-Ⅱ型尤甚。AD 组、抑郁症组及 NC 组在潜伏期 M₂及波幅 M₁、M₂差异有显著性（P<0.05～0.01）。与 NC 组相比,抑郁症组波幅降低和潜伏期延迟。AD 组呈同样趋势。结论 CNV 是评定 AD 患者和抑郁症患者大脑综合功能的有效工具,值得临床推广应用。更多还原

【Abstract】 Objective In order to investigate the variations of contingent negative variations（CNV）of patients with anxiety disorder（AD）and depression,the present study was initiated.Methods Event-related potentials were recorded from 37 AD patients using a Nicolet Bravo Instrument,and were compared with those of 32 patients with depression and 36 normal controls（NC）.Results AD and depression patients presented irregular CNV wave- form,especially CNV-Ⅱ type.A significant difference of CNV among 3 groups was found in latency and amplitudes （M₂,M₂）（P<0.05～0.01）.Compared with NC group,depression group showed delayed M₂ latency and de- creased M₂ amplitude（P<0.05～0.01）.Compared with NC group,AD group showed delayed increased amplitude. Conclusion CNV is a useful tool for assessing the brain malfunction of AD and depression,and its clinical applica- tion is recommended.更多还原