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强迫症患者的Quisi睡眠监测研究
Monitoring study of quisi in patients with obsessive-compulsive disorder
【摘要】 目的探讨强迫症患者 Quisi 睡眠参数的变化特征。方法应用德国 Quisi 仪对27例强迫症(OCD)患者的 Quisi 进行全夜监测,并与33名正常受试者(NC)对照。结果与正常成人组比较,OCD 组 Quisi 主要表现为 REM 睡眠潜伏期前移,REM 活动度,REM 强度,REM 密度和第1阶段睡眠均增加以及睡眠潜伏期延迟和睡眠效率降低。结论在缺乏相关设备的基层医院,Quisi 技术可用于对强迫症的检测。
【Abstract】 Objective To assess the changes of the whole night Quisi in patients with obsessive-compulsive dis- order(OCD).Methods The all-night Quisi was recorded from 27 patients with depression and 33 normal controls, by using a Germany Quisi Instrument.Results Compared with normal subjects,OCD patients showed significantly shortened REM latency(NC:87.8±11.7,OCD group:57.7±21.4,P<0.01),increased REM activity(NC: 80.7±9.2,OCD group:119.8±54.5,P<0.01),increased REM intensity(NC:17.8%+2.3%,OCD group: 27.8%±13.4%,P<0.01),increased REM density(NC:95.7%±8.1%,OCD group:147.4%±69.2%,P< 0.05),increased stage 1 sleep(NC:9.1%±1.9%,OCD group:19.9%±11.4%,P<0.01),delayed sleep la- tency,and reduced sleep efficiency.Conclusion In hospitals without relevant equipment,Quisi technique may be used for assay of OCD.
【Key words】 obsessive-compulsive disorder; electrophysiology; sleep; rapid eye movement;
- 【文献出处】 神经病学与神经康复学杂志 ,Journal of Neurology and Neurorehabilitation , 编辑部邮箱 ,2006年04期
- 【分类号】R749.7
- 【下载频次】29