【摘要】 目的研究颈动脉粥样硬化斑块与脑梗死及其危险因素的关系。方法应用HP彩色超声仪对153例脑梗死患者的颈动脉进行检测,分为脑梗死侧组和非脑梗死侧组进行颈动脉粥样硬化斑块发生率和狭窄程度的比较,并将患者的病史、个人史和生化检查与颈动脉粥样硬化斑块的关系进行多因素分析。结果脑梗死侧组颈动脉粥样硬化斑块和软斑的发生率较非脑梗死侧组高,两组之间有显著性差异(P<0.05),多元Logistic回归分析显示年龄、低密度脂蛋白、纤维蛋白原和糖基化血红蛋白是影响脑梗死患者颈动脉粥样硬化斑块的独立危险因素。结论颈动脉粥样硬化斑块与脑梗死之间存在着密切关系,多种因素影响颈动脉粥样硬化斑块的形成。更多还原

【Abstract】 Objective To investigate the relationship among carotid plaque, cerebral infarction and the relative factors. Methods Carotid atrherosclerosis was assessed by color Doppler ultrasongraphy in 153 cases of cerebral infarction and the characters of carotid atherosclersis and degree of constriction was compared between cerebral infarction group (191 cases) and control group (115 cases). The history of past illness, personal history, and laboratory examinations was analyzed between two groups and multivariate regress analysis of its related factors was done. Results The occurrence rates of carotid plaques and carotid artery malacoplakias were higher in cerebral infarction artery than those in non-cerebral arteries ( P < 0.05 ). The multivariate Logistic regress analysis age、 low density lipoprotein (LDL)、 fibrinogen and glycated hemoglobin were independent factors that influence carotid atherosclerosis. Conclusions There is a positive ralationship between carotid atherosclerosis and cerebral infarction, and a lot of factors can influence the occurrence of carotid plaques.更多还原