【摘要】 目的:观察脂肝清颗粒对脂肪肝模型大鼠的影响。方法:用乙硫氨酸性脂肪肝、酒精性脂肪肝模型,观察脂肝清颗粒对血脂代谢、肝内脂代谢、肝组织改变、肝功能和肝内脂肪变细胞百分比等的影响。结果:脂肝清颗粒可使乙硫氨酸大鼠血CHO、TG显著升高,肝内TG、Gn显著降低,肝脏脂肪变性和颗粒变性显著改善。可使酒精性脂肪肝大鼠血CHO、TG、LDL显著降低,HDL显著升高,肝内TG、Gn含量显著降低,肝脏脂肪变性、颗粒变性、纤维组织增生显著改善。结论:脂肝清颗粒有明显抗脂肪肝作用。更多还原

【Abstract】 AIM: To observe the Zhiganqing Grannules’effect on various fatty liver rats. Methods: The model of ethionine type fatty liver and the model of alcohol type fatty liver were used to observe different doses of Zhiganqing Granules’ effect on blood fat metabolism, inside liver fat metabolism, liver tissue change, liver function and inside liver lipocyte proportion. Results: Zhiganqing Granules can evidently lower CHO, TG in blood and TG、Gn of liver in ethionine rats, improve the transformation of fatty liver and granula. Zhiganqing Grannules can evidently decrease CHO, TG, LDL of blood, lower TG,Gn of liver , enhance HDL in alcohol type fatty liver rats. It can also improve the transformation of fatty liver and granula and the hyperplasia of fiber texture. It can be shown in these graphs that in every model Zhiganqing Granules do have remarkable effect on lowering the proportion of lipocytes area and enhancing the proportion of normal liver cells area, so it do have the effect on lowering the ratio of lipocytes area versus normal liver cells area by image manipulation on pathological slice-up of liver’s tissues.Conclusions: Zhiganqing Granule have the effect in lowering fat of liver.更多还原