【摘要】 目的　了解我院出生缺陷发生情况及分布特征 ,分析可能的原因。方法　对 1993年 1月至 2 0 0 2年 12月在我院分娩的出生缺陷儿进行分析。结果　 (1)出生缺陷率为 1.6 5 %。 (2 )出生缺陷中以神经管畸形居多 ,农村畸形率高于城市 ;35岁以上产妇中畸形率高。 (3) 98年后城市出生缺陷率显著降低 ,而农村 98年前、后出生缺陷率无显著变化。 (4)出生缺陷的发生与围产儿性别无关。结论　加强围产保健宣传、健全农村基层妇幼保健网和提高孕产妇保健意识是降低出生缺陷发生率的有效措施。更多还原

【Abstract】 Objective: To study the occurrence, distributing and related factors of birth defect. Methods: A retrospective review of all perinatal infant born in our hospital from 1993 to 2002 was analysed. Results: (1)The birth defect rate in our hospital was 1.65%. (2)The incidence of NTDwas in the first place. There was higher morbidity in rural areas than in urban areas.The birth defect rate was found to be associated with gestation age. (3)The morbidity of birth defect has decreased significantly in urban areas between 1998-2002 and 1992-1997. (4)The occurrence of birth defect was unrelated to sex difference.Conclusion To strengthen perinatal health education, to improve consciousness of maternal health care are effective measures to decrease the birth defect rate.更多还原