节点文献
气相色谱法测定通立康膏中樟脑、异龙脑、龙脑、桂皮醛、丁香酚的含量
Determination of Camphor,Isoborneol,Borneol,Cinnamaldehyde and Eugenol in Tonglikang Ointment by Gas Chromatography
【摘要】 目的建立气相色谱法测定通立康膏中的樟脑、异龙脑、龙脑、桂皮醛、丁香酚的含量。方法以聚乙二醇为固定液相,涂布浓度为100%,FID检测,检测器温度为250℃,采用程序升温法。结果GC法测定五组分的分离度和线性关系良好,平均回收率分别为:樟脑96.21%,RSD=1.03%;异龙脑97.34%,RSD=0.99%;龙脑97.07%,RSD=1.00%;桂皮醛96.00%,RSD=1.37%;丁香酚100.99%,RSD=1.07%。结论该方法灵敏、快速、准确,可作为通立康膏的质量控制方法。
【Abstract】 Objective To establish a gas chromatography(GC) method for the determination of camphor,isoborneol,borneol,cinnamaldehyde and eugenol in Tonglikang ointment.Methods Polyethylene glycol with 100 %of application concentration was used as stationary liquid phase.GC was equipped with FID detector at 250 ℃and programmed heating method was applied.Results The resolution and the linearity were good with the recovery rate of camphor being 96.21 %(RSD=1.03 %),isoborneol 97.34 %(RSD=0.99 %),borneol 97.07 %(RSD=1.00 %),cinnamaldehyde 96.00 %(RSD=1.37 %),and eugenol 100.99 %(RSD=1.07 %) respectively.Conclusion The method is convenient,rapid and accurate.It can be used to control the quality of Tonglikang ointment.
【Key words】 Tonglikang Ointment； Camphor； Isoborneol； Borneol； Cinnamaldehyde； Eugenol； GC； Content determination；
- 【文献出处】 中药新药与临床药理 ,Traditional Chinese Drug Research & Clinical Pharmacology , 编辑部邮箱 ,2005年01期
- 【分类号】R286
- 【被引频次】12
- 【下载频次】264