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紫外分光光度法测定盐酸川芎嗪氯化钠注射液中盐酸川芎嗪含量
Determination the Content of Ligustrazine Hydrochloride in Ligustrazine Hydrochloride and Sodium Chloride Injection by Ultraviolet Spectrophotometry
【摘要】 目的:建立盐酸川芎嗪氯化钠注射液中盐酸川芎嗪的含量检测方法。方法:采用紫外分光光度法,检测波长为295nm。结果:盐酸川芎嗪在3.0-15.0μg·ml-1范围内呈良好线性关系(r=1.0000,n=5),回收率为100.3%,RSD为0.65%(n=5)。结论:本法操作简便、快捷,结果准确,尤适用于药厂、医院对该制剂半成品的质量控制和快速分析。
【Abstract】 Objective: To establish a method for determining the content of ligustrazine hydrochloride in ligustrazine hydrochloride and sodium chloride injection. Method: The ultraviolet spectrophotometry was used. The detecting wavelength was at 295 nm. Result: The linear range of ligustrazine hydrochloride was 3.0-15.0 μg·ml-1 (r = 1.000 0,n =5). The average recovery was 100.3% ,RSD = 0.65%. Conclusion: This method is simple, rapid, and accurate, and suitable for the the content determination of this injection.
【关键词】 川芎嗪氯化钠;
盐酸;
川芎嗪;
紫外分光光度法;
【Key words】 Ligustrazine hydrochloride and sodium chloride injection; Ultraviolet spectnophotometry;
【Key words】 Ligustrazine hydrochloride and sodium chloride injection; Ultraviolet spectnophotometry;
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2005年01期
- 【分类号】R286
- 【被引频次】6
- 【下载频次】183