【摘要】 目的研究乙型肝炎后肝硬化病人凝血功能变化与Child-Pugh肝功能分级的关系。方法测定88例乙型肝炎后肝硬化病人与28例健康者的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原。结果乙型肝炎后肝硬化病人存在不同程度凝血功能障碍,PT、APTT、Fbg水平与对照比较,差异有非常显著性,检测结果显示A、B、C级之间PT、APTT、Fbg相互比较,差异有非常显著性。结论乙型肝炎后肝硬化病血浆PT、APTT、Fbg,可作为判定病变程度的指标,可对预后作出有价值的判断,为治疗提供依据。更多还原

【Abstract】 [Objective] To study the relationship between blood coagulation function changes and Child-Pugh liver function grades among patients with post hepatitis B cirrhosis.[Methods] PT,APTT and Fbg of 88 patients and 28 healthy people were determined respectively.[Results] Patients with post hepatitis B cirrhosis had various degrees of dysfunction of blood coagulation.Significant difference was found in PT,APTT and Fbg compared with that of the control group.Significant difference was also found among different grades.[Conclusion] The plasma PT, APTT and Fbg are useful markers for determining the degrees of the disease,it also provide basis for the treatment.更多还原