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EB病毒感染者肿瘤坏死因子及白介素2水平研究

Clinical Study on Serum TNF-α and IL-2 Level in the Cases Infected of EB Virus

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【作者】 周小军田道法徐庆文何健生孙一帆孔祥廉郭亿莲冯炳毅

【Author】 Zhou Xiao-jun~1,Tian Dao-fa~2,Xu Qing-wen~1,HE Jian-sheng,SUN Yi-fan,KONG Xiang-lian,GUO Yi-lian,FENG Bing-yi(1.Zhongshan Hospital Affiliated to Guangzhou University of TCM,Zhongshan,528400,Guangdong China;2.Hunan College of Traditional Chinese Nedicine,Changsha,410007,Hunan,China)

【机构】 广州中医药大学中山附属医院湖南中医学院广州中医药大学中山附属医院 广东中山528400湖南长沙410007广东中山528400广东中山528400

【摘要】 目的:研究鼻咽癌高发区EB病毒感染者肿瘤坏死因子(TNF-α)及白介素2(IL-2)水平。方法:免疫酶法检测血清EBVCA-IgA确定EB病毒感染者44例为观察组,以健康人18例作为对照组,ELISA法测定血清TNF-α及IL-2水平;比较其血清TNF-α及IL-2水平。结果:EB病毒感染者及健康对照者TNF-α分别为(37.5±18.7)pg/mL及(23.2±9.6)pg/mL,P<0.01;而IL-2分别为(14.4±7.1)pg/mL及(18.7±6.4)pg/mL,P<0.05。结论:EB病毒感染者肿瘤坏死因子水平增高而白介素2水平低下。

【Abstract】 Objective:To test the serum TNF-α and IL-2 level in the cases infected of EB Virus.Methods:The EB Virus titer was tested as immunoenzyme method and the serum TNF-α and IL-2 were tested by ELISA methods.The 44 EB Virus infected cases were the observation group,and the 18 health people were the control group.Results:The health people serum TNF-α level is (23.2±9.6)pg/mL,and The EBV- infected cases serum TNF-α level is (37.5±18.7)pg/mL, P<0.01.The health people serum IL-2 level is (18.7±6.4)pg/mL,and The EBV-infected cases serum IL-2 level is (14.4±7.1)pg/mL,P<0.05.Conclusion:The cases infected of EB Virus has higher serum TNF-α level and lower serum IL-2 level.

【关键词】 EB病毒感染肿瘤坏死因子白介素2
【Key words】 EB Virus infectionTNF-αIL-2
【基金】 中山市科委重点课题资助项目(2003A58)
  • 【文献出处】 中医药学刊 ,Study Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2005年10期
  • 【分类号】R739.63
  • 【被引频次】5
  • 【下载频次】190
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