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降血脂新药匹伐他汀
A new lipid-lowering agent:pitavastatin
【摘要】 匹伐他汀是新一代他汀类药物。该药不仅具有较强的HMG-CoA还原酶抑制作用,而且呈肝细胞选择性,药动学性质优异,安全性好,已被制药界誉为是“超级他汀”。现就匹伐他汀的药理及临床应用进行综述。
【Abstract】 Pitavastatin is the most recently approved statin. It not only competitively inhibits HMG-CoA reductase,but also has liver-selective action, thus being regarded as "superstatins". This paper reviews pharmacology and pharmacotherapy of pitavastatin.
【关键词】 匹伐他汀;
HMG-CoA还原酶抑制剂;
降血脂;
【Key words】 pitavastatin; HMG-CoA reductase inhibitor; lipid-lowering;
【Key words】 pitavastatin; HMG-CoA reductase inhibitor; lipid-lowering;
- 【文献出处】 中国新药杂志 ,Chinese New Drugs Journal , 编辑部邮箱 ,2005年04期
- 【分类号】R972
- 【被引频次】52
- 【下载频次】967