节点文献
九江市HIV-流行毒株基因序列测定和亚型分析
Subtype and sequence analysis of HIV-1 strains in Jiujiang
【摘要】 目的:了解九江市H IV-1流行毒株的亚型分布情况。方法:对采集的6份九江市H IV-1感染者的血浆样品进行RT-PCR扩增,获得GAG基因的核酸片断进行核苷酸序列分析。结果:在6份样品中发现B′亚型H IV-1毒株四株,B亚型和A/E重组亚型H IV-1毒株各一株。结论:H IV-1流行毒株亚型在九江市分布情况复杂,防控形势严峻。
【Abstract】 Objective:To study the epidemic situation and characteristic of subtypes of HIV-1 strains prevalent in Jiujiang.Methods:Six DNA fragments of HIV-1 GAG gene were amplified by RT-PCR from blood plasma obtained from six HIV-1 carrier in Jiujiang The genes were sequenced and analyzed.Results:There were four strains of HIV-1 subtype B′,one strain of HIV-1 subtype B and one strain of HIV-1 recombining subtype A/E.Conclusion:There is complex epidemic situation of subtypes of HIV-1 strains prevalent in Jiujiang.The situation of HIV control and prevention is austere.
【Key words】 HIV-1; GAG gene; Gene sequence determine; Subtype analysis;
- 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2005年12期
- 【分类号】R346
- 【被引频次】1
- 【下载频次】47