【摘要】 目的　评估拉米夫定治疗慢性乙型肝炎的经济学价值。方法　运用临床试验和相关文献资料,采用Markov模型对拉米夫定治疗慢性乙型肝炎进行经济学评价。结果　与安慰剂相比,拉米夫定每延长1年寿命,所需医疗费用在2 5 0 0 0元以下,疗程较长者的拉米夫定治疗与疗程较短者相比,每延长1年寿命所需的医疗费用在3 85 0 0元以下。结论　拉米夫定具有成本效果,疗程越长,成本效果越好。更多还原

【Abstract】 Objective To assess the long-term cost-effectiveness of lamivudine for treament of chronic hepatitis B.Methods Markov model was employed to conduct the economic evaluation based on the data retrieved from clinical trial results and literatures. Results The incremental medical cost of having lamivudine available was less than 25,000 RMB per year of life saved as opposed to placebo and less than 38,500 RMB per year of life saved compared to shorter treatment duration of lamivudine.Conclusion Lamivudine is of cost effectiveness. Longer treatment duration lamivudine, more cost effective.更多还原