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牛奶中阿莫西林残留的检测及其消除规律的研究

Study on the depletion of amoxicillin residues in the cow milk

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【作者】 侯东军吴银良刘素英

【Author】 HOU Dong-jun,WU Yin-liang,LIU Su-ying(Inspection Center of Agricultural Ministry for Domestic Animal Product,Beijing 100026;China)

【机构】 农业部畜禽产品质量监督检验测试中心农业部畜禽产品质量监督检验测试中心 北京100026北京100026

【摘要】 选用2组健康正常泌乳奶牛注射阿莫西林,剂量分别为1 mL/20 kg体重(正常剂量组)和2 mL/20 kg体重(加倍剂量组),连续用药5 d后开始取奶样检测其中的阿莫西林残留量。休药0 h,正常剂量组奶样中阿莫西林残留量为9.0μg/kg,加倍剂量组奶样中阿莫西林残留量为16.9μg/kg。随着休药时间的延长,奶样中阿莫西林残留量迅速降低。

【Abstract】 Four healthy cows of the first group were administered amoxicillin with a dosage of 1 mL/20 kg BW one time per day for five days successivly.Four healthy cows of the second group were administered with double dosage in the same way.The milk samples from eight cows were collected at 0,6,12 h and 1,2,3 days after the last dose.The residues of amoxicillin were detected by high performance liquid chromatography.The results showed that the depletion of amoxicillin in milk was fast,the residues of the two groups at 0 h were 9.0 and 16.9 μg/kg respectively,no residue was detected at 36 h.

【关键词】 阿莫西林奶牛休药期验证
【Key words】 amoxicillincowresiduedepletion
【基金】 国家科技攻关项目(2002BA906A75)
  • 【文献出处】 中国兽药杂志 ,Chinese Journal of Veterinary Drug , 编辑部邮箱 ,2005年12期
  • 【分类号】S859.84
  • 【被引频次】10
  • 【下载频次】269
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