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黄芪多糖和淫羊藿多糖对培养细胞增殖和衰老的影响
Effects of Astragalus Polysaccharide and Epimedium Polysaccharide on Proliferation and Decrepitude of CEF
【摘要】 将安全浓度范围内的黄芪多糖(astragaluspolysaccharide,APS)和淫羊藿多糖(epimediumpolysaccharide,EPS)分别加入到培养12h和24h的鸡胚成纤维细胞(CEF)中,测定加药后CEF增殖率和成层率的动态变化。结果表明,2种多糖均能促进细胞增殖和延缓细胞衰老,EPS的作用强于APS,具有一定的量效、时效关系。
【Abstract】 The astragalus polysaccharide(APS) and epimedium polysaccharide(EPS) within safety concentration were respectively added into chick embryo fibroblast(CEF) medium and cultured for 12 and 24 hours. The proliferation and stratification rates of CEF were dynamically determined after administration. The results showed that two polysaccharides could promote proliferation and postpone decrepitude of the cell, efficacy of EPS was stronger than that of APS, and there were dose-and thme-effect relationships.
【关键词】 黄芪多糖(APS)；
淫羊藿多糖(EPS)；
鸡胚成纤维细胞(CEF)；
增殖；
衰老；
【Key words】 astragalus polysaccharide(APS)； epimedium polysaccharide(EPS)； chick embryo fibroblast(CEF)； proliferation； decrepitude；
【Key words】 astragalus polysaccharide(APS)； epimedium polysaccharide(EPS)； chick embryo fibroblast(CEF)； proliferation； decrepitude；
【基金】 国家自然科学基金资助项目(30070566)
- 【文献出处】 中国兽医学报 ,Chinese Journal of Veterinary , 编辑部邮箱 ,2005年03期
- 【分类号】S853.7
- 【被引频次】37
- 【下载频次】426