【摘要】 采用低 VE和添加不饱和脂肪酸的日粮饲喂 1日龄雏鸡 ,建立了 VE缺乏实验动物模型 ,检测其脑组织 (大脑和小脑 )中丙二醛和活性氧的含量及神经细胞凋亡的数量 ,并进行了相关性分析。结果表明 ,VE缺乏雏鸡脑组织中的丙二醛和活性氧含量及神经细胞凋亡的数量显著高于健康对照组 (P<0 .0 5 ) ,细胞凋亡的数量与大、小脑组织中丙二醛和活性氧含量呈显著的相关性 (相关系数分别为 0 .75 0 2、0 .815 5和 0 .8170、0 .6 931) ,说明 VE缺乏雏鸡脑组织处于氧化应激状态 ,并可诱导脑神经细胞凋亡更多还原

【Abstract】 The trial chicken model with the V_E deficiency was set up by using low content of V_E and supplying unsaturated fatty acid in the feed.The content of MDA and active oxygen and quantity of neurocyte apoptosis were measured in cerebrum and cerebellum of trial chicken and correlation analysis was carried out in this experiment.The results showed that the content of MDA and active oxygen and quantity of neurocyte apoptosis of the brain tissuses of chicken with V_E defficiency were significantly higher than those of control ones and there were significant correlation between the content of MDA and active oxygen and quantity of apoptosis of neurocyte.The results indicated that the brain tissues of chicken with the V_E deficiency were in the state of super oxidant stress,which induced apoptosis of neurocyte.更多还原