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Graves病中磁运动诱发电位与肌电图的临床价值

Clinical value of magnetic motor evoked potentials and electromyography in Graves disease

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【作者】 林少达郭美云陈小华黄芷荷

【Author】 LIN Shao-da,GUO Mei-yun,CHEN X iao-hua,HUANG Zhi-he.Department of Endorcrinology,The First Affiliated Hospita l of Shantou University Medical College,Shantou,Guangdong,515041,China

【机构】 汕头大学医学院第一附属医院内分泌科汕头大学医学院第二附属医院电生理室汕头大学医学院第二附属医院电生理室 515041广东汕头515041广东汕头

【摘要】 目的应用磁运动诱发电位(MEP)和肌电图(EMG)探讨Graves病(GD)神经肌肉受损临床价值。方法GD病组46例行MEP和EMG检查;正常对照组50例行MEP检查,31例行EMG检查。结果46例GD患者神经肌肉症状26例(56·5%),MEP异常38例(82·6%),EMG异常39例(84·8%);以MEP异常判断EMG异常敏感性87·2%,特异性89·5%;以EMG异常判断MEP异常敏感性89·5%,特异性87·2%。结论两种方法对CTM诊断异常率、敏感性和特异性相似;MEP主要对神经源性损害敏感,EMG主要对肌源性损害敏感,具互补性。

【Abstract】 Objective To investigate the ne uromuscular changes and clinical value of Graves disease(GD) by using magnetic m otor evoked potentials(MEP) and electromyography(EMG).Methods M EP and EMG were measured in 46 cases of GD and 50 normal controls in which 31 go t EMG measured.Results In 46 GD patients,26 cases had neuromusc ular symptoms or signs(56.5%),38 with abnormal MEP(82.6%),and 39 with abnormal E MG(84.8%).The sensitivity of electromyography deduced from abnormal MEP was 87.2 %,and speciality was 89.5%;The sensitivity of MEP deduced from abnormal EMG was 89.5%,and speciality was 87.2%.Conclusion Measure of MEP and EM G show comparability in abnormity,sensitivity and speciality of CTM;MEP is mainl y sensitive in neural damage and EMG is mainly sensitive in muscular damage,bein g complement for each other.

【基金】 广东省医学科研课题(A2000467)
  • 【文献出处】 中国基层医药 ,Chinese Journal of Primary Medicine Pharmacy , 编辑部邮箱 ,2005年08期
  • 【分类号】R581
  • 【下载频次】30
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