【摘要】 目的探讨双探头18F-FDG显像对原发不明转移瘤(UPT)的诊断价值。方法应用双探头18F-FDG显像检查70例UPT患者,并根据FDG浓聚诊断原发灶。结果根据FDG显像阳性诊断为原发灶58例,其中肺癌42例,全部患者均经病理证实。原发灶诊断符合率为82.9%,以肺癌最常见。FDG显像阴性12例(17.1%),进一步检查诊断原发灶5例,随访中诊断原发灶1例,未能诊断原发灶6例。结论双探头18F-FDG显像诊断UPT原发灶是一种简便、快速、无创、灵敏的方法。原发灶以肺癌最常见。FDG显像原发灶诊断符合率达80%以上,可作为UPT的首选诊断方法。更多还原

【Abstract】 Objective To investigate the diagnostic value of dual-head 18 F-fluorodeoxyglucose ( 18 F-FDG) imaging in metastatic lesion with unknown primary tumour (UPT). Methods Seventy patients with UPT underwent dual-head 18 F-FDG imaging after iv 18 F-FDG 1.85 MBq/kg. The primary tumour was diagnosed according to the FDG uptake and T/N value. Results Of the 70 patients, the primary tumour was identified by positive FDG imaging and finally confirmed pathologically in 58 patients (82.9%), and 12 patients had a negative FDG imaging (17.1%). Forty-two of the 58 positive patients were found to have lung cancer (72.4%) . Among the 12 negative patients, their primary tumour was then identified by other diagnostic procedures in 5 patients (41.7%), in 1 patient,the primary site was detected during follow-up, however, the primary tumour was never detected in the rest 6 patients. Conclusion Dual-probe 18 F-FDG imaging is a simple, quick, non-invasive and sensitive technique with an accuracy over 80% in the diagnosis of unknown primary tumour. The lung is found to be the most frequent primary site. Dual-probe 18 F-FDG imaging can be recommended as the first diagnostic choice for UPT.更多还原