【摘要】 目的分析我院2003年8月~2004年8月检出的铜绿假单胞菌(PAE)的血清学分型及药敏结果,为临床合理选用抗菌药物提供依据。方法对各种送检标本按《全国临床检验操作规程》进行菌种鉴定及药敏试验,对分离到的59株PAE用日本生研公司的分型血清进行血清学分型。结果59株PAE中可分型的有56株,分离率为94.9%,对PAE保持较高抗菌活性且耐药率<30%的抗菌药物有阿米卡星、亚胺培南、环丙沙星、庆大霉素、左氧氟沙星、哌拉西林/他巴唑等;不同血清型对各种抗菌药物的敏感率有所不同。结论PAE对常用抗菌药物的耐药率较高,不同血清型的耐药率有差异,对PAE进行血清学分型及耐药分析,有助于临床根据药敏结果选用抗菌药物,可有效控制和减缓细菌耐药性的增长。更多还原

【Abstract】 OBJECTIVE To explore serotype an d drug-sensitive test of Pseudomonas aeruginosa(PAE) from Aug 2003 to Aug 2004,so as to provide basis for clinical antibiotic selection. METHODS The type of bacteria was determin ed and drug sensitive test was performed.Then,59 isolated strains of acquired PAE for serotype was conducted. RESULTS Among 59 strains,56 could be di stinguished,the distinction rate was 94.9%,those antibiotics such as amikacin sulfate,imipenem-cilastatin sodium,ciprofloxacin,gentamicin sulfate,levof loxacin and piperacillin sodium were very effective to PAE with the drug-resist ant rate below 30%.Furthermore,different serotype of PA needed different sensi tive antibiotics. CONCLUSIONS PAE is drug-resistant to co mmon antibiotics.The drug-resistance and serotype study help to find out the s ensitive drugs for clinical application,thus to bring down the growth of drug-resistance rate of bacteria.更多还原