【摘要】 目的检测江苏省淋病奈瑟菌(淋菌)临床分离株对几种抗生素的药敏情况,并初步探讨耐药因素。方法采用琼脂稀释法检测淋菌对青霉素、四环素、环丙沙星、头孢曲松、头孢吡肟、头孢噻肟、大观霉素、左氧氟沙星的MIC。结果淋菌对3种头孢类药物敏感率均为100%,对大观霉素敏感率为94·7%,对四环素敏感率为1·1%,而对青霉素和环丙沙星100%耐药。结论江苏省淋菌临床分离株对青霉素、四环素、环丙沙星耐药严重,对目前的一线药物(头孢类药物和大观霉素)敏感,但应重视大观霉素耐药株的出现。更多还原

【Abstract】 Objective To analyse the antibiotics susceptibility result of Neisseria gonorrhoeae(N.g) isolates.Method 95 strains of N.g were performed the in-vitro susceptibility test.MICs of penicillin, tetracycline, ciprofloxacin, levofloxacin, ceftriaxone, cefotaxime, cefepime, and spectinomycin were determined by agar dilution.Results Almost all of the N.g strains were susceptible to the first-line antibiotics used for treating the infection. The resistance rate to ciprofloxacin, tetracycline and penicillin were 100%, 78.9% and 68.4% respectively.Conclusion Although N.g is susceptible to first-line antibiotics used for treating the infections at the clinics, the situation of resistance to penicillin, tetracycline and ciprofloxacin is very serious.更多还原