【摘要】 目的　报道1例原发于颈部淋巴结的并指树突细胞肉瘤(IDCS)。临床资料　41岁男性患者,以颈左侧淋巴结肿大为首发症状,同时有外周血常规检测结果和骨髓象异常。病理切片和免疫组化检查结果证实为IDCS,采用ABVD(阿霉素、博来霉素、长春花碱、氮烯脒胺)方案化疗后,临床症状获得明显改善,但未能抑制肿瘤浸润。结论　IDCS作为一种罕见的恶性肿瘤,其临床表现缺乏特异性,病理形态亦无特征性变化,容易与其它组织/树突细胞肿瘤混淆,免疫组化与电镜检查是确诊的关键方法。IDCS恶性程度高。目前多采用非霍奇金淋巴瘤的化疗方案,但治疗反应差异很大。更多还原

【Abstract】 Objective To report a case of interdigitating dendritic cell sarcoma(IDCS). Patient material The patient was a 41-year-old man with a lymph node bulging in the left neck. Laboratory examination of peripheral blood and bone marrow was abnormal. The diagnosis of IDCS was made by immunohistochemistry and electron microscopy. Treatment of this patient with ABVD regimen (adriamycin, bleomycin, vinblastin, dacarbazine) resulted in obvious improvement, but did not control the tumor infitration. Conclusion IDCS has no distinctive clinical or pathohistological characteristics. Immunohistochemistry and electron microscopy are crucial in distinguishing it from other histiocytic/dendritic cell neoplasms. IDCS displays an aggressive behaviour, and the responses to chemotherapy are variable.更多还原