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电视胸腔镜胸腺扩大切除治疗重症肌无力107例临床分析

Video-assisted thoracoscopic extended thymectomy for myasthenia gravis: analysis of 107 cases

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【作者】 刘会平李剑锋吴怡成谢明儒刘永恒姜冠潮刘军王俊

【Author】 LIU Hui-ping~*, )LI Jian-feng,WU Yi-cheng,XIE Ming-ru, LIU Yong-heng, JIANG Guan-chao, LIU Jun, WANG Jun.(~*Division of) Thoracic Surgery, Chang Gung Memorial Hospital,Chang Gung University,Taibei,Taiwan Province, China

【机构】 长庚大学医学院长庚纪念医院胸外科北京大学人民医院胸外科暨胸部微创中心北京大学人民医院胸外科暨胸部微创中心 中国台湾省台北中国台湾省台北

【摘要】 目的探讨电视胸腔镜下胸腺扩大切除术治疗重症肌无力的临床效果。方法对1995年6月至2004年6月,台湾长庚纪念医院胸外科和北京大学人民医院胸外科根据临床表现及肌电图检查诊断证实为单纯重症肌无力,行电视胸腔镜胸腺完整切除及前纵隔脂肪组织廓清术治疗的107例患者的临床资料进行回顾分析。结果术后随访1~98个月,完全缓解34例,改善55例,全组完全缓解及改善率为83%,无手术死亡病例。结论电视胸腔镜下手术切除胸腺及前纵隔脂肪组织治疗重症肌无力临床效果良好,安全,创伤较小。

【Abstract】 Objective To evaluate the results of video-assisted thoracoscopic extended thymectomy for myasthenia gravis. Methods We retrospectively reviewed data from 107 patients received thoracoscopic extended thymectomy from June 1995 to June 2004. All patients had confirmed diagnosis of myasthenia gravis by clinical manifestation and electromyogram. Thoracoscopic extended thymectomy as well as dissection of all fatty tissue anterior to the pericardium was performed.Results During a follow-up of 1—98 months, symptom was significantly improved in 83% of patients, including 34 patients experienced complete remission. There was no postoperative mortality. Conclusion Favorable results of video-assisted thoracoscopic extended thymectomy can be achieved in patients with myasthenia gravis. The technique is safe and minimally invasive.

  • 【文献出处】 中华外科杂志 ,Chinese Journal of Surgery , 编辑部邮箱 ,2005年10期
  • 【分类号】R655
  • 【被引频次】45
  • 【下载频次】279
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