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探讨P-gp和GST-π在肺鳞癌中的表达及临床意义

Disguss the expression and clinical significance of P-gp and GST-π in the lung squamous cell carcinoma

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【作者】 钟良清

【Author】 Zhong Liangqing. The Department of pathology, Gaozhou City People’s Hospital, Guangdong 525200

【机构】 广东省高州市人民医院 525200

【摘要】 目的探讨P-gp和GST-π在肺鳞状细胞癌中的表达与临床意义。方法应用免疫组织化学技术,检测87例肺鳞状细胞癌中P-gp和GST-π多药耐药的表达。结果87例肺鳞状细胞癌中P-gp和GST-π表达的阳性标记与肺鳞状细胞癌临床化疗有相关性(P<0.05)。结论P-gp和GST-π联合表达与肺鳞状细胞癌化疗密切相关,检测P-gp和GST-π对鳞状细胞癌化疗方案的制定具有重要的意义。

【Abstract】 Objective To discuss the expression of P- gp and GST- πand clinical significance in the lung squamous cell carcinoma. Methods With application of immunity histochemistry technology, jerque 87 cases P- gp and GST-πmanifold medicine were able to bear or endure the expression in the lung squamous cell carcinoma. Results The 87 cases P- gp and GST- π,expression of masculine sign in the lung squamous cell carcinoma and clinical abc warfare have pertinence. Conclu- sion The P- gp and GST- πcombining expression have osculation correlation with the lung squamous cell carcinoma abc war- fare. Jerquing P- gp and GST- πin lung squamous cell carcinoma cure blue print of constitute possess important significance.

  • 【文献出处】 中国现代医药杂志 ,Medical Journal of Casc , 编辑部邮箱 ,2005年04期
  • 【分类号】R734.2
  • 【被引频次】1
  • 【下载频次】30
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