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乳腺导管内癌及伴微浸润的病理和临床特征

The clinical and pathological characteristics of breast ductal carcinoma in situ and with microinvasion

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【作者】 李文萍王颀张安秦许娟赖日权张江宇陈中杨杨剑敏

【Author】 LI Wen-ping , WANG Qi, ZHANG An-qin, XU Juan, LAI Ri-quan, ZHANG Jiang-yu, CHEN Zhong-yang, YANG Jian-min. Breast Disease Center, Guangdong Women and Children Hospital, Guangzhou 510010, China

【机构】 广东省妇儿医院乳腺病中心广东省妇儿医院病理科广州军区广州总医院病理科广东省妇儿医院乳腺病中心 510010510010

【摘要】 目的 研究导管内癌(ductalcarcinomainsitu ,DCIS)及伴微浸润(DCISwithmicroinvasion ,DCIS MI)患者的病理与临床特征。方法 对1999年6月至2 0 0 3年6月收治的4 1例DCIS及Ⅰ、Ⅱ型DCIS MI患者的临床和病理学特点进行回顾性研究。结果 DCIS及Ⅰ、Ⅱ型DCIS MI的病理学特点不同;首发症状中,9 76 %的患者仅表现为乳腺摄影钙化灶(5 0 %为DCIS) ;乳腺摄影检查诊断符合率为80 % ,Ⅱ型DCIS MI乳腺摄影表现为肿块和腺体紊乱的比例为33 3% ,高于DCIS和Ⅰ型DCIS MI;5 7%的患者表现为乳头溢液,乳管内视镜诊断符合率为95 6 5 % ;局部复发2例,均为Ⅱ型DCIS MI患者。结论 DCIS与Ⅰ型、Ⅱ型DCIS MI病理和临床表现各有特点,因而预后也不同。

【Abstract】 Objective To study the clinical and pathological characteristics of breast ductal carcinoma in situ (DCIS) and with microinvasion (DCIS-MI). Methods From June 1999 to June 2003, a total of 41 patients with DCIS and DCIS-MI patients were retrospectively studied. Results Pathology varies between DCIS type Ⅰ, type Ⅱ and DCIS-MI patients. Mammographic calcification was the only presenting symptom in 9.76% of patients with DCIS accounting for 50% of these cases. The accordance rate of mammography with final diagnosis was 80%, and 33.3% of mammography in DCIS-MI type 2 showed mass or chaos of gland construction. The initial symptom in 57% of patients was nipple discharge. For fiberoptic ductoscopy, the accordance rate was 95.65%. There were two local recurrent cases in DCIS-MI type 2. Conclusion Breast ductal carcinoma in situ and with microinvasion had their own characteristics, including different prognosis.

  • 【文献出处】 中华普通外科杂志 ,Chinese Journal of General Surgery , 编辑部邮箱 ,2005年04期
  • 【分类号】R737.9
  • 【被引频次】26
  • 【下载频次】329
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