节点文献
梅岭霉素的分离纯化
An Approach to Separate and Purify Meilingmycin
【摘要】 利用南昌霉素在较低pH介质中加热时易降解而梅岭霉素较稳定的性质,结合溶剂萃取法除去杂质,纯化梅岭霉素。经全波长扫描、HPLC和质谱分析等,推测梅岭霉素同系物的分子结构。
【Abstract】 Meilingmycin was separated and purified by taking the advantage of the different properties of nanchangmycin and meilingmycin. The former degraded when heating at low pH condition while the latter kept intact. The impurities formed after treatment were removed by solvent extraction. On the basis of results of the full wave scanning, HPLC determination and mass spectrum analysis, the molecular formulas of meilingmycin homologues had been proposed.
【关键词】 梅岭霉素;
南昌霉素;
同系物;
纯化;
萃取;
【Key words】 meilingmycin; nanchangmycin; homologue; purification; solvent extraction;
【Key words】 meilingmycin; nanchangmycin; homologue; purification; solvent extraction;
【基金】 国家“十五”攻关项目(2001BA708B07-05)
- 【文献出处】 中国医药工业杂志 ,Chinese Journal of Pharmaceuticals , 编辑部邮箱 ,2005年05期
- 【分类号】TQ465
- 【被引频次】3
- 【下载频次】131