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敏咳清口服液对卵蛋白造模大鼠血液、支气管-肺灌洗液中IL-6,IL-8,ET-1,TXB2的影响
Influence of Minkeqing oral liquid on IL-6,IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin
【摘要】 目的:观察敏咳清口服液治疗小儿过敏性咳嗽的疗效、探讨其细胞分子生物学作用机理。方法:将大鼠用卵蛋白吸入法造模、观测敏咳清口服液对模型动物血液、支气管-肺灌洗液中IL-6,IL-8,ET-1,TXB2的影响。结果:敏咳清口服液能降低模型动物血液、支气管-肺灌洗液中IL-6,IL-8,ET-1,TXB2的水平。结论:敏咳清口服液具有明显的抑制炎性介质释放的作用。
【Abstract】 Objective: To observe the effect on infantile allergic cough with Minkeqing oral liquid (Minkeqing) and to study its cell molecular biologic mechanism. Method: The rat model was induced by inhalating ovalbumin; then the effects of Minkeqing on IL-6, IL-8, ET-1, TX-B2 in the blood and the bronchoalveolar lavage fluid (BALF) of the animal model were obsered. Result: Minkeqing could reduce the levels of IL-6,IL-8,ET-1 .Tx-B2 in the blood and BALF of the animal model. Conclusion: Minkeqing has the significant function of inhibiting the release of inflammatory mediums.
【Key words】 Minkeqing oral liquid； allergic cough； IL-6； IL-8； ET-1； TX-B2；
- 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2005年14期
- 【分类号】R285.5
- 【被引频次】3
- 【下载频次】134