【摘要】 目的:筛选水溶性和水不溶性载体的种类、配比,研究缓释滴丸剂的成型处方。方法:以圆整度、硬度、料液的黏度、流动性、易滴制程度、累计释放百分数等为考察指标,采用正交设计试验对精制芎归缓释滴丸的成型处方进行优选。结果与结论:按照选定的处方既能有一定的速释量,还能保证10h持续释药80%以上,达到了释药设计目的。更多还原

【Abstract】 Objective: To optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied. Method: An orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop. Result and Conclusion: According to the final optimal formula, the amount of drug release can be detected instantly, while remaining over 80% at 10 h.更多还原