【摘要】 目的:研究分析炉甘石炮制方法和机理。方法:采用热重分析技术和纳米技术分析并合成炉甘石的组成成分,以四环素为对照,测定不同粒径的炉甘石及其纳米成分的抑菌活性。结果:炉甘石主要含碳酸锌,炮制使部分碳酸锌分解为氧化锌,且粒径变小。炉甘石抑菌活性主要取决于氧化锌的含量和粒径大小,与碳酸锌无关。氧化锌含量越高、粒径越小,抑菌活性越强。结论:氧化锌含量和粒径大小可做为炉甘石炮制的主要指标。更多还原

【Abstract】 Objective: To study processing method and mechanism of Calamine. Method: Thermogravimetry analysis method and nano-technology were adopted to analyze and synthesize the components in Calamine, Tetracycline was took as the comparison drug to determine the antibacterial activity of Calamine and its components. Result: A part of zinc carbonate in Calamine was decomposed into zinc oxide when processing, and the particle size was smaller than before. The antibacterial activity of Calamine is decided by the content and particle size of zinc oxide,and has nothing with zinc carbonate. The more content and the smaller particle size of zinc oxide,the more powerful antibacterial activity of Calamine. Conclusion: The content and the particle size of zinc oxide can be the important targets in the processing of Calamine.更多还原