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立体定向放射治疗肝门部胆管癌疗效分析

Analysis of efficacy of 3D-SRT in treatment of hilar cholangiocarcinoma

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【作者】 蔡鹏龙志雄陈桂民孙劲松李玉新杨士勇

【Author】 CAI Peng,LONG Zhi-xiong,CHEN Gui-min,et al(Jingmen Second People’s Hospital,Hubei Province 448000,China)

【机构】 湖北省荆门市第二人民医院湖北省荆门市第二人民医院 448000448000448000

【摘要】 目的探讨肝门部胆管癌立体定向放射治疗的疗效。方法17例因内科或外科原因不能手术或患者不同意手术的肝门部胆管癌采用立体定向放射治疗,单次剂量4~8 Gy(中位剂量5.6 Gy),总剂量40~60 Gy(中位剂量48 Gy)。结果CR 8例,PR 9例,总有效率为100.0%;1年生存率为94.1%(16/17)。结论立体定向放疗是肝门部胆管癌的有效治疗方法。

【Abstract】 Objective To assess the efficacy of three-dimensional sterotactic radiotherapy(3D-SRT) in treament of patients with hilar cholangiocarcinoma.Methods Seventeen cases of in operable hilar cholangiocarcinoma were treated with 3D-SRT to an average total dose of 48 Gy(40-60 Gy),at a median fractional dose 5.6 Gy(4-8 Gy) for 5-15 fractions,once every day or every two days.Results CR was observed in 8 cases,PR in 9 cases.The overall response rate was 100.0% and 1-year survival rate was 94.1%.Conclusion 3D-SRT is an effective treatment for cholangiocarcinoma.

  • 【文献出处】 中国肿瘤临床与康复 ,Chinese Journal of Clinical Oncology and Rehabilitation , 编辑部邮箱 ,2005年05期
  • 【分类号】R735.8;
  • 【被引频次】5
  • 【下载频次】58
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