节点文献

计算机辅助成像分析法在微丸圆整度评价中的应用

Evaluation of pellets sphericity using computer assistant image analysis

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 王俊周寅曹志娟赖顺果裴元英

【Author】 WANG Jun, ZHOU Yin, CAO Zhi-juan, LAI Shun-guo, PEI Yuan-ying ( Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 200032, China; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai 200032, China; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200032, China)

【机构】 复旦大学药学院药剂学教研室复旦大学药学院药物分析学教研室复旦大学药学院药理学教研室复旦大学药学院药剂学教研室 上海 200032上海 200032上海 200032

【摘要】 目的建立计算机辅助的成像分析平台,分别考察市售的空白丸芯和自制的GBE微丸的圆整度。方法采用计算机辅助的成像分析法。结果空白丸芯和GBE微丸的纵横比(AR)值分别为1.16±0.09,1.14±0.09(n=25),形状因子(eR)值分别为0.56±0.12,0.62±0.14(n=25)。结论该方法能够直观、简便地评价微丸的圆整度,所制备的GBE微丸圆整度较好。

【Abstract】 OBJECTIVE To establish a computer assistant image system for investigating the pellets sphericity. METHODS The computer assistant image analysis was applied. RESULTS The aspect ratios of the blank and GBE pellets were 1.16±0.09,1.14±0.09(n = 25), and the shape factors (eR) were 0.56 ± 0.12,0.62 ±0.14( n = 25) .CONCLUSION The pellets sphericity can be evaluated directly and conveniently by the computer assistant image analysis. The sphericity of GBE pellets was desirable.

【关键词】 计算机辅助成像分析微丸圆整度
【Key words】 computer assistantimage analysispelletsphericity
  • 【文献出处】 中国药学杂志 ,Chinese Pharmaceutical Journal , 编辑部邮箱 ,2005年07期
  • 【分类号】TP391.7
  • 【被引频次】10
  • 【下载频次】169
节点文献中: 

本文链接的文献网络图示:

本文的引文网络