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复感康颗粒质量控制方法研究
Study of Quality Control Method for Fugankang Granules
【摘要】 目的:建立复感康颗粒的质量控制方法。方法:采用薄层色谱法对复感康颗粒中黄芪、白术、陈皮进行定性鉴别;采用高效液相色谱-蒸发光散射检测器法测定复感康颗粒中黄芪甲苷的含量。结果:在薄层色谱中可鉴别出黄芪、白术、陈皮;黄芪甲苷进样量在1.306μg~13.060μg范围内线性关系良好(r=0.9997),平均加样回收率为97.62%(RSD=1.72%)。结论:本方法简便、准确、重现性好,可用于复感康颗粒的质量控制。
【Abstract】 OBJECTIVE:To establish the quality control method for fugankang granules.METHODS:Radix Astragali,Atr actylodes Macrocephala,Pericarpium Citri Reticulatae in fugankang granules were identified by TLC and the content of astraˉgaloside in fugankang granules was determined by HPLC-ELSD method.RESULTS:Radix Astragali,Atractylodes Macroˉcephala,Pericarpium Citri Reticulatae could be identified by TLC;Astragaloside showed good linear relationship within the range of1.306μg~13.060μg(r=0.9997),the average recovery was 97.62%(RSD=1.72%).CONCLUSION:The method is simple,accurate and with good reproducibility,which can be used as quality control for fugankang granules.
【Key words】 Fugankang granules; Quality control; TLC; HPLC-ELSD;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2005年16期
- 【分类号】R286.0
- 【被引频次】3
- 【下载频次】96