【摘要】 目的:评价茵栀黄注射液治疗黄疸型病毒性肝炎临床研究论文的方法学质量。方法:对相关文献77篇,按照CochraneReviewer’sHandbook4.2.2评价指南的质量评价标准进行质量评价、分析。结果:仅有4篇随机对照试验符合纳入标准,其中随机对照研究(RCT)2篇,半随机对照研究(CCT)2篇;4篇研究均为低质量的研究(C级),存在选择性偏倚、实施偏倚、测量偏倚及损耗性偏倚的高度可能性。结论:要获得临床茵栀黄注射液治疗黄疸型病毒性肝炎的可靠证据,尚需进行更多高质量的随机对照研究。更多还原

【Abstract】 OBJECTIVE:To evaluate the quality of the methodology of clinical research on Yinzhihuang injection in the treatment of icteruc virus hepatitis.METHODS:The methodology quality of77pertinent literatures was evaluated and analyzed according to the quality assessment criteria in the evaluation manual of Cochrane Reviewer’s Handbook 4.2.2.RESULTS:Only 4 literatures were up to the related standards,2 of which were randomized controlled trials(RCT)and other 2 were semi-randomized controlled trials(CCT).All of the 4 studies were low quality(Grade C)researches,in which the biases on selectivity,practice,measurement and wastage were highly possible.CONCLUSION:More randomized controlled trials of high quality are needed to obtain reliable evidences on Yinzhihuang injection in the treatment of icteric virus hepatitis.更多还原