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注射用头孢西丁钠与甲硝唑注射液的配伍稳定性考察

Stability of Cefoxitin Sodium for Injection Compatible with Metronidazole Injection Fluid

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【作者】 黄震华黄云英黄鹤鸣黄丽敏

【Author】 HUANG Zhenhua,HUANG Yunying,HUANG Heming,HUANG Limin(Dept.Of Pharmacy,The Shen-zhen People’s Hospital,Shenzhen518020,China)

【机构】 深圳市人民医院药学部深圳市人民医院药学部 深圳市518020深圳市518020深圳市518020

【摘要】 目的:考察注射用头孢西丁钠与甲硝唑注射液的配伍稳定性。方法:采用紫外分光光度法测定注射用头孢西丁钠与甲硝唑注射液配伍后溶液在常温下放置4h内不同时间的最大吸收峰峰位和吸收度,并观察溶液的色泽及测定其pH值。结果:配伍液的吸收峰位、吸收度、色泽及pH值均无明显变化。结论:注射用头孢西丁钠与甲硝唑注射液配伍后在常温下4h内稳定。

【Abstract】 OBJECTIVE:To evaluate the stability of cefoxitin sodium for injection compatible with metronidazole injection fluid.METHODS:Cefoxitin sodium for injection was compatible with metronidazole injection fluid and the solution was stored ordinary temperature for4hours,the maximum absorption peak and absorbance of the solution were determined by UV,and the color of the solution was observed,and its pH value was determined.RESULTS:There were no significant changes in absorp-tion peak,absorbance,color and pH value of the compatible solution.CONCLUSION:Cefoxitin sodium for injection is com-patible with metronidazole injection fluid,and the compatible solution remains stable at ordinary temperature for4hours.

  • 【分类号】R942
  • 【被引频次】9
  • 【下载频次】154
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