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不同方法提取淫羊藿苷的正交试验研究

Orthogonal Design Experiment on the Extracting of Icariin by Different Means

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【作者】 杨帆钟桂雄赵洪普林春燕温晓清何小玲

【Author】 YANG Fan(College of Pharmacy,Guangdong University of Pharmacy,Guangzhou 510224,China)ZHONG Guixiong(Liming Pharmaceutical Factory,IVZON Pharmaceutical Group Inc,Shaoguan 512028,Ch_ina)ZHAO Hongpu(The Guangdong Hospital of TCM,Guangzhou 510000,China)LIN Chunyan,WEN Xiaoqing,HE Xiaoling(2000 Grad in College of Pharmacy,Guangdong University of Pharmacy, Guangzhou 510224,China)

【机构】 广东药学院药科学院丽珠集团利民制药厂广东省中医院广东药学院药学系广东药学院药学系 广州市510224韶关市512028广州市5100002000级学生广州市510224广州市510224

【摘要】 目的 :筛选淫羊藿苷最佳提取方法和提取工艺条件。方法 :分别采用乙醇回流法和乙醇超声波法提取淫羊藿苷 ,并以淫羊藿苷的含量为指标 ,对提取工艺中的乙醇用量、乙醇浓度、提取时间、提取次数等因素进行考察。结果与结论 :乙醇回流法对淫羊藿苷的提取效果优于乙醇超声法 ;乙醇回流法提取淫羊藿苷的最佳提取工艺条件是用8倍药材量的60 %乙醇提取淫羊藿3次 ,每次40min。

【Abstract】 OBJECTIVE:To optimize the extraction and preparation technics of icariin by orthogonal design.METHODS:The icariin was extracted by the ethanol reflux and the ethanol ultrasonic extracting process respectively;the quantity and concentration of ethanol,extracting time and extracting times were investigated with the content of the icariin as a indicator.RESULTS & CONCLUSION:The ethanol refluxing process is better than the ethanol ultrasonic process in the extraction of icariin.The most optimistic condition of extracting of icariin in ethanol refluxing extracting process was as follows:the crude drug was extracted for 3 times(40min/time)by using 60% ethanol,which is 8 times of the amount of the crude drug.

【基金】 广东省中医药管理局基金资助项目 (102082)
  • 【分类号】TQ461
  • 【被引频次】18
  • 【下载频次】590
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