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复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效观察

Clinical Effects of SNMCTM on Liver Injury Induced by Anti-Tumor Medicine

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【作者】 郑滢宋方闻庄学龙吴悦义

【Author】 ZHENG Ying,ZHUANG Xuelong,WU Yueyi(Tumor Hospital,Medical College of Shantou University,Shantou515031,China) SONG Fangwen(Nanda College of Guangzhou Medical College,Guangzhou510320,China)

【机构】 广东汕头大学医学院附属肿瘤医院广州医学院南大学院广东汕头大学医学院附属肿瘤医院 汕头市515031广州市510320汕头市515031汕头市515031

【摘要】 目的 :观察复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效。方法 :将60例应用抗肿瘤药导致肝功能损害的患者随机分成治疗组 (32例 )和对照组 (28例 ) ,治疗组在对照组用药基础上加用复方甘草酸苷。结果 :治疗组在丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素的改善程度上均明显优于对照组 (P<0.01)。结论 :复方甘草酸苷有很好的保肝降酶、抗炎、免疫调节作用 ,未见不良反应 ,用药安全 ,推荐用于治疗抗肿瘤药导致的肝损害。

【Abstract】 OBJECTIVE:To observe the clinical effects of Stronger Neo-Minophagen C(SNMC)in the treatment of liver function damage caused by anti-tumor medicine.METHODS:60cases of liver injury caused by anti-tumor medicine were randomly divided into the treatment group(32cases)and the control group(28cases).SNMC injection was given in the treatment group as a supplement to the primary therapy in the control group.RESULTS:The treatment group with SNMC showed significantly greater improvement than the control group in the liver functions(ALT,AST,T.BIL)(P<0.01).CONC_ LUSION:SNMC is effective for liver function damage caused by anti-tumor medicine for its protective,anti-inflammatory,and immunity-regulatory function.SNMC is also a secure medicine with less side effects and therefore is recommendable for treatment of liver injury caused by anti-tumor medicine.

  • 【分类号】R730.5
  • 【被引频次】11
  • 【下载频次】203
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