【摘要】 目的:研究兰科植物球花石斛的化学成分,以探明其有效成分并为制定中药石斛质量标准提供科学依据。方法:采用硅胶柱层析、SephadexLH-20及RP-18等色谱技术分离纯化化合物,根据光谱数据鉴定结构。结果:从球花石斛95%乙醇提取物中分离得到香豆素类、肉桂酸苷类、蒽醌苷类等12个化合物,分别鉴定为:香豆素(1),泽兰内酯(2),东莨菪内酯(3),东莨菪苷(4),xeroboside(5),densifloroside(6),isodensi-floroside(7),大黄酚-8-O-葡萄糖苷(8),木栓酮(9),24(R)-6β-hydroxy-24-ethlcholest-4-en-3-one(10),对羟基反式肉桂酸三十烷基酯(11),软酯酸1-甘油单酯(12)。结论:化合物4,5,8,12为首次从石斛属中分离得到,其它化合物均为首次从球花石斛中分离得到。更多还原

【Abstract】 AIM: To investigate the chemical constituents of Dendr ob ium thyrsiflorum Rchb.f. and to evaluate the quality of “Herba Dendrobii” (S hihu, in Chinese) more roundly. METHOD: Compounds were isolated by silic a gel, Sephadex LH-20 and RP-C 18 column chromatography and identified ma inly by spectral data. RESULT: Twelve compounds including coumar ins, cinnamyl glucosides, anthraquinone gucoside et al were obtained and identif ied as coumarin(1), ayapin (2), scopoletin ( 3), scopolin (4), xeroboside (5), de nsifloroside (6), isodensifloside (7), chrysopha nein (8), friedelin (9), 24(R)-6β-hydroxy -24-ethlcholest-4-en-3-one(10), defuscin (11 ), hexadecanoic acid 2,3-dihydroxypropyl ester (12). CONCLUSION: Compounds 4, 5, 8 and 12 were firstly isolated from the Dendrobium thyr siflorum, and the others were obtained from this plant for the first time.更多还原