【摘要】 目的:为阐明番荔枝科瓜馥木属植物瓜馥木治疗关节炎和抗癌的有效成分,我们对瓜馥木化学成分进行系统研究。方法:通过各种层析手段分离21个化合物,应用波谱方法鉴定其中16个化合物。结果:其结构分别为calycinine(1),Nmethyl-2,3,6-trimethoxymorphinandien-7-one(2),aristololactamAⅢa(3),xylopine(4),crebanine(5),isolaureline(6),asimilobine(7),duguevanine(8),corytuberine(9),aristololactamAⅡ(10),isoboldine(11),goniothalactam(12),glaucine(13),(-)-epicatechin(14),aristololactamBⅡ(15),7′-(3′,4′-dihydroxyphenyl)-N-{(4-methoxyphenyl)ethyl}propenamide(16)。结论:化合物3、5、12、15为首次从该种植物分得,化合物6、7、8、9、11、13、14、16为首次从该属植物中分得。更多还原

【Abstract】 AIM:To study the active constituents of the stems or root of Fissistigma oldhamii.METHOD:Compounds were isolated by means of column chromatography,and the structures were identified on the basis of MS and NMR spectral analysis.RESULT:Sixteen compounds were isolated and identified as:calycinine(1),N-methyl-2,3,6-trimethoxy morphinandien-7-one(2),aristololactam AⅢa(3),xylopine(4),crebanine(5),isolaureline(6),asimilobine(7),duguevanine(8),corytuberine(9),aristololactam AⅡ(10),isoboldine(11),goniothalactam(12),glaucine(13),(-)-epicatechin(14),aristololactam BⅡ(15),7′-(3′,4′-dihydroxyphenyl)-N-{(4-methoxyphenyl)ethyl}propenamide(16).CONCLUSION:Compounds 3,5,12,15 were isolated from this plant for the first time; compounds 6,7,8,9,11,13,14,16 were isolated from Fissistigma for the first time.更多还原