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病毒调控宿主免疫反应的研究进展

Advances of researches on viruses regulating host immune responses

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【作者】 沈小燕丛国正常惠芸罗自清王建华谢庆阁

【Author】 SHEN Xiao-yan~1,2 , CONG Guo-zheng~2 , CHANG Hui-yun~1 , LUO Zi-qing~3 , WANG Jian-hua~2 , XIE Qing-ge~1 (1. Key Laboratory of Animal Virology, Ministry of Agriculture/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Lanzhou,730046,China; 2. College of Animal Science and Technology, Northwest Sci-Tech University of Agriculture and Forestry, Yangling 712100,China; 3. Jianzha County Station of Animal Husbandry and Veterinary Medicine, Qinghai Province,Jianzha 813000,China)

【机构】 中国农业科学院兰州兽医研究所农业部畜禽病毒病重点开放实验室青海省尖扎县畜牧兽医站西北农林科技大学动物科技学院中国农业科学院兰州兽医研究所农业部畜禽病毒病重点开放实验室 甘肃兰州730046陕西杨凌712100甘肃兰州730046青海尖扎813000甘肃兰州730046

【摘要】 病毒感染宿主后,针对宿主免疫反应的特点和薄弱环节,形成了多种方式拮抗宿主的免疫防御。论述了病毒抑制体液免疫及其抑制或调节细胞因子活性的过程和方式,旨在从分子水平上阐明病毒逃避免疫应答的机理。

【Abstract】 Viruses will resist host immunoprotection in various ways in the light of characterizations and weak stages of host immune responses after infecting into the hosts. The processes and ways of inhi-biting host humoral immunity, interfering or regulating cytokines functions of viruses were discussed at molecular levels to illuminate mechanisms of viruses escaping immune responses from the hosts.

【关键词】 病毒感染调控免疫反应
【Key words】 virusinfectionregulation