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4种小鼠的寒、热体质研究

Study of cold or hot constitution of four species of mice

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【作者】 陈小野张宇鹏张晓娟邹世洁蒋小丽王丽芳王肃崔成德欧阳海燕刁作斌

【Author】 CHEN Xiaoye ,et al.China Academy of Traditional Chinese Medicine ,Beijing 100700

【机构】 中国中医研究院中国中医研究院 北京100700北京100700北京100700

【摘要】 [目的]研究4种品系小鼠的寒、热体质。[方法]8~9周龄昆明、BALB/c、C57BL/6J、ICR小鼠,以及4~5周龄昆明小鼠,同步系统检测其生物学特性,然后以统一的评价标准评价4种品系小鼠的寒、热体质。并对BALB/c小鼠给予参桂理中丸和利血平做药物反证。[结果]①4~5周龄昆明小鼠与8~9周龄昆明小鼠比较体质明显偏热;②BALB/c小鼠与C57BL/6J小鼠比较体质偏寒;③8~9周龄雄性BALB/c小鼠、雄性和雌性C57BL/6J小鼠与8~9周龄相应性别昆明小鼠比较体质无明显差异;8~9周龄雌性BALB/c小鼠与8~9周龄雌性昆明小鼠比较体质偏寒;④8~9周龄ICR小鼠与8~9周龄BALB/c小鼠、C57BL/6J小鼠比较体质偏热;8~9周龄雄性ICR小鼠与8~9周龄雄性昆明小鼠比较体质偏热。[结论]4种品系小鼠存在寒、热体质差异。

【Abstract】 [Objective] To research cold or hot constitution of four species of mouse.[Methods] eight to nine-week-old kunming mice BALB/c mice , C57BL/6Jmice , ICR mice and four to five-week-old kunming mice were inspected their biological characteristics with a simultaneous systematic inspection.The four species of mice are assessed by a same criterion about their constitution whether it is prone to cold or hot. The satime BALB/c mice treated with pill of Shenguilizhong and reserpine were used negtive control. [Results] 1. Four to five-week old kunming mice is compared with eight to nine-week-old kunming mice.The former constitution is obviously prone to hot; 2. Comparsion between BALB/c mice and C57BL/6J mice,the former is prone to cold; 3. Eight to nine-week-old male BALB/c mice and C57BL/6J mice (include male and female) are compared with eight to nine-week-old corresponding sex kunming mice respectively.Each group do not have obivious difference. Eight to nine-week-old female BALB/c mice is compared with eight to nine-week-old female kunming mice. The former is prone to cold. 4. Eight to nine-week-old ICR mice is prone to hotter than eight to nine-week-old BALB/c mice and C57BL/6J mice; The eight to nine-week-old male ICR mice is prone to hotter than the eight to nine-week-old male kunming mice.[Conclusion] The four species of mice have the difference of cold or hot constitution.

【关键词】 小鼠体质
【Key words】 mousecoldhotconstitution
  • 【文献出处】 中国实验动物学报 ,Acta Laboratorium Animalis Scientia Sinica , 编辑部邮箱 ,2005年S1期
  • 【分类号】S853;
  • 【被引频次】5
  • 【下载频次】128
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