【摘要】 目的探讨常规雾化+制霉菌素钠雾化吸入对气管切开患者下呼吸道感染的疗效。方法90例气管切开后的患者随机分为三组,分别采用不同的药物进行雾化吸入,并对其呼吸道分泌物进行细菌和真菌培养。结果常规雾化+制霉菌素组真菌感染的发生率显著低于常规雾化组(P<0.01),而与制霉菌素组无明显差别(P<0.05);细菌感染的发生率则与常规雾化组无明显差异(P>0.05)。结论制霉菌素钠与庆大霉素和α-糜蛋白酶交替雾化吸入,对防治气管切开术后下呼吸道感染有一定疗效。更多还原

【Abstract】 Objective To explore the curative effect of inhalation of routine atomized liquid and atomized nystatin on lower respiratory tract infection in the patients undergoing tracheotomy. Method Ninety patients after tracheotomy were randomly divided into three groups, i.e. group A (inhaling the routine atomized liquid containing α-chymotrypsin, gentamycin sulfate and saline), group B (inhaling the atomized nystatin) and group C (inhaling the routine atomized liquid and atomized nystatin). The culture of bacteria and epiphytes of the sputum was performed. Result The rate of epiphytes infection was significantly lower in group B and C than that in group A (P<0.01). The rate of the bacteria infection in group A was significantly lower than that in group B (P<0.01) and similar to that in group C (P>0.05). Conclusion The curative and preventive effect of the alternate inhalation of atomized nystatin, and gentamicin sulfate plus a-chymotrypsin on the lower respiratory tract infection (caused by both the epiphytes and bacteria) is good in the patients umdergoing tracheotomy.[更多还原