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感染传染性支气管炎病毒后雏鸡血液中一氧化氮合酶和一氧化氮的动态观察

Changes of Serum NO and NOS Content in Chickens Infected with Avian Infectious Bronchitis Virus

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【作者】 彭芳珍佘锐萍靳红马卫明胡艳欣雷鸣王淑臻

【Author】 Peng Fangzhen1,She Ruiping1,Jin Hong1,Ma Weiming1,Hu Yanxin1,Lei Ming1,Wan g Shuzhen2 (1.College of Veterinary Medicine,China Agricultural University, Beijing 100094; 2.Beijing Municipal Supply and Marketing Institute, Beijing 100076)

【机构】 中国农业大学动物医学院北京市供销学校 北京100094北京100094北京100076

【摘要】 80只14日龄SPF鸡随机均分为实验组和对照组,实验组用鸡传染性支气管炎病毒M41株人工感染,感染后1、3、5、7、11、15天分别测定感染组及对照组血清中一氧化氮合酶(NOS)和一氧化氮(NO)的含量,研究NO在鸡传染性支气管炎发病过程中的作用。结果表明:实验组血清NOS含量自攻毒后第3天上升,一直持续至鸡群恢复期,但与对照组无显著差异。实验组血清NO含量在攻毒后第3天也开始上升,攻毒后第5、7、11天血清NO含量显著高于对照组,此后血清中NO含量上升趋势有所减缓。提示NO可能参与调节了传染性支气管炎的发生发展过程。

【Abstract】 Eighty 14-day-old chickens were randomly divided into two groups. 4 0 chickens were used for infection and 40 chickens were served as control. Serum NO and NOS contents were measured at day 1,3,5,7,11,15 after infection,respecti vely.The results indicated that serum NOS content of experiment group started to increase at day 3 after infection,but the difference between experiment and con trol group was not significant. Serum NO content of experiment group also starte d to increase at day 3 after infection and significantly higher than that of co ntrol group at day 5,7,11 after infection. The results implied that NO may regul ate the occurrence and development of avian infectious bronchitis.

【基金】 北京市自然科学基金(6022102);国家自然科学基金(30270995,30471301)
  • 【分类号】S852.3
  • 【被引频次】4
  • 【下载频次】93
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