【摘要】 目的了解罹患严重急性呼吸综合征(SARS)的医务人员康复期的肺部情况,以及本病对肺功能的影响。方法选取确诊为SARS的医务人员76例,出院后进行症状问卷调查、胸部CT、肺功能测定及SaO2检查。结果出院后主要表现为乏力67例(882%),脱发57例(750%),骨关节疼痛54例(711%),气短31例(408%),痤疮20例(263%),心悸18例(237%),下肢水肿15例(197%),月经紊乱12例(占女性患者194%)。胸部CT异常41例(539%),主要表现为弥漫或散在的磨玻璃样改变、弥漫或局限的小叶间隔增厚或纤维条索影,其中5例合并胸膜结节(66%),3例合并牵引性支气管扩张(39%)。出院(71±14)d时76例SARS医务人员中4例表现弥散功能降低(53%),1例为轻度阻塞性通气功能降低,1例为呼气中期流速降低,40d后对上述6例进行肺功能复查,其中仅1例仍为轻度阻塞性通气功能降低,其余4例弥散功能、1例呼气中期流速均恢复正常。共16例有通气储备不佳(211%),结果为57%～85%,平均(795±70)%。出院后76例SaO2测定结果为96%～100%,平均(985±09)%。结论SARS治愈后仍有部分后遗症状,胸部CT有部分异常,肺功能总体恢复良好,未遗留明显功能异常。更多还原

【Abstract】 Objective To study the pulmonary function changes and CT appearance in medical workers who had severe acute respiratory syndrome （SARS）.Methods Clinical questionnaire,pulmonary function test,chest CT,and SaO₂ test were performed in 76 SARS medical workers after they were discharged from the hospital.Results The main symptoms among the 76 medical workers were:weakness （67 cases,88.2%）,alopecia （57 cases,75.0%）,osteodynia and arthrodynia（54 cases,71.1%）,dyspnea （31 cases,40.8%）,acne （20 cases,26.3%）,palpitate （18 cases,23.7%）,edema of lower extremity （15 cases,19.7%）,and menstruous disturbance （12 cases,19.4% of female）.41 cases （53.9%） had abnormal CT findings,which included diffused or scattered ground glass-like images,diffused or localized thickness of interlobular septum or fibrous bundles,pleural nodus （5 cases,6.6%） and tractional bronchiectasis （3 cases,3.9%）.4 cases （5.3%） of the 76 medical workers had impaired diffusion capacity,1 case demonstrated mild lowered obstructive ventilation function and 1 case had decreased MMEF after （71±14） days discharged from hospital.Re-examing the 6 cases after 40 days revealed only 1 case still had mild obstructive ventilation function disturbance while the other 5 cases had recovered.16 cases （21.1%） demonstrated impaired ventilatory reserve with a range of 57% to 85% and an average of （79.5±7.0）%.The average SaO_<sup>2 of 76 medical workers were 96%～100% （98.5±0.9）% after discharge.Conclusion The patients recovered from SARS have some sequels and some abnormal CT manifestations,however,their pulmonary function recovered in general without permanent impairment.更多还原