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大连地区新生儿弓形虫感染的免疫学检测
Study on status of toxoplasma infection and immunology detection in new-born babies
【摘要】 目的 探讨大连地区新生儿弓形虫感染的情况。方法 采用酶联免疫吸附试验三联诊断法对 93例新生儿脐带血清标本进行弓形虫感染的血清学检测。结果 新生儿弓形虫各单项检测阳性率分别为循环抗原 (CAg)4 3%、IgM 2 2 %、IgG 1 5 1 %,新生儿弓形虫平均感染率为 1 9 4%,其中近期感染率为 5 4%。 结论 新生儿弓形虫感染的危险性很高 ,应开展孕妇血清学监测及时采取措施 ,有效地预防先天性弓形虫感染。
【Abstract】 Objective To investigate the status of toxoplasma (Tox) infection in new-born babies. Methods Enzym-linked immunosorbent assay (ELISA) was used to detect circulating antigen (CAg),special antibodies IgM and IgG in fetal umbilical blood.Results Among the 93 cases,4 were TOX-CAg positive(4.3%),2 were TOX-IgM positive (2.2%) and 14 were TOX-IgG positive (15.1%) in newborn infants.the overall prevalence rate of toxoplasmosis among the newborn infants was 19.4% (18/93);the rate of acute infection was 5.4%.Conclusion Newborn infants are at the high risk of toxoplasma infection,about 5.4% fetus will get acute infection from their mothers before they give birth.Therefore,Sero-epidemiologic survey in pregnant women show an important significance in better child-bearing.
【Key words】 txoplasma; new-born babies; circulating antigen(CAg); special antibody; ELISA;
- 【文献出处】 中国公共卫生 ,China Public Health , 编辑部邮箱 ,2005年02期
- 【分类号】R722.1
- 【被引频次】6
- 【下载频次】75