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大连地区新生儿弓形虫感染的免疫学检测

Study on status of toxoplasma infection and immunology detection in new-born babies

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【作者】 韩美君李雅杰李晓慧张丹

【Author】 HAN Meijun,LI Yajie,LI Xiaohui,et al.Department of Pathogenic Biology ,Medical College,Dalian University(Dalian 116622,China)

【机构】 大连大学医学院病原生物学教研室大连大学医学院病原生物学教研室 116622116622116622

【摘要】 目的 探讨大连地区新生儿弓形虫感染的情况。方法 采用酶联免疫吸附试验三联诊断法对 93例新生儿脐带血清标本进行弓形虫感染的血清学检测。结果 新生儿弓形虫各单项检测阳性率分别为循环抗原 (CAg)4 3%、IgM 2 2 %、IgG 1 5 1 %,新生儿弓形虫平均感染率为 1 9 4%,其中近期感染率为 5 4%。 结论 新生儿弓形虫感染的危险性很高 ,应开展孕妇血清学监测及时采取措施 ,有效地预防先天性弓形虫感染。

【Abstract】 Objective To investigate the status of toxoplasma (Tox) infection in new-born babies. Methods Enzym-linked immunosorbent assay (ELISA) was used to detect circulating antigen (CAg),special antibodies IgM and IgG in fetal umbilical blood.Results Among the 93 cases,4 were TOX-CAg positive(4.3%),2 were TOX-IgM positive (2.2%) and 14 were TOX-IgG positive (15.1%) in newborn infants.the overall prevalence rate of toxoplasmosis among the newborn infants was 19.4% (18/93);the rate of acute infection was 5.4%.Conclusion Newborn infants are at the high risk of toxoplasma infection,about 5.4% fetus will get acute infection from their mothers before they give birth.Therefore,Sero-epidemiologic survey in pregnant women show an important significance in better child-bearing.

  • 【文献出处】 中国公共卫生 ,China Public Health , 编辑部邮箱 ,2005年02期
  • 【分类号】R722.1
  • 【被引频次】6
  • 【下载频次】75
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