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鲍曼不动杆菌院内感染调查及耐药分析

Clinical investigation and resistance analysis of acinetobacter

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【作者】 王倩邓宇欣刘阳江伶

【Author】 WANG Qian,DENG Yuxin,LIU Yang,et al.The First Affiliated Hospital of China Medical Uniersity(Shenyang 110001,China)

【机构】 中国医科大学第一临床学院检验科沈铁分局沈北医院妇科辽宁电力中心医院妇产科 沈阳110001沈阳110001

【摘要】 目的调查鲍曼不动杆菌院内感染分布特点及耐药性。方法常规细菌培养方法,细菌鉴定采用法国生物梅里埃鉴定系统,药敏试验采用琼脂纸片扩散法。结果鲍曼不动杆菌最常出现于痰标本中,占78.7%,其次是脓汁和分泌物标本;鲍曼不动杆菌感染以病房为主,尤以重症监护病房(ICU)病房分布最多,其次是神经外科病房;该菌耐药现象严重,耐药率较低的抗菌药物有碳青霉烯类药物、含酶抑制剂复合制剂及左旋氧氟沙星。结论应合理选择使用抗菌药物,加强医院环境和人员消毒,控制鲍曼不动杆菌在医院内的定值和播散。

【Abstract】 Objective To investigate the clinical distribution and resistane of Acinetobacter Baumanii.Methods Routine bacteria culture and France BioMerieux identification system were adopted for bacteria identification.Susceptibility was tested by Kirby-Bauer method.Results For specimen from which Acinetobacter baumanii were examined,sputum accounted for 78.7%,being the highest percentage.Then were pus and secretion.Acinetobacter baumanii was mainly distributed at ward,especially at ICU ward.Then was neurosurgery ward.The resistance of Acinetobacter baumanii was serious.At the present,the antibiotic drugs which had the low resistance ratio were carbapenems,β-lactam/β-lactamase inhibitor combinations and levofloxacin.Conclusion It was important for clinic to use antibiotic drugs reasonably.The disinfection should be strengthened for hospital environment and medical staff in order to control existance and spread of Acinetobacter baumanii in hospital.

【关键词】 鲍曼不动杆菌抗菌药物耐药
【Key words】 acinetobacter baumaniiantibiotic drugresistance
  • 【文献出处】 中国公共卫生 ,China Public Health , 编辑部邮箱 ,2005年01期
  • 【分类号】R446.5
  • 【被引频次】16
  • 【下载频次】134
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