【摘要】 目的:调查上海地区泌尿生殖道感染者支原体的检出情况及体外药敏结果。方法:用IST2试剂盒对1642例疑为支原体感染的标本进行解脲脲原体(Uu)、人型支原体(M H)的培养、鉴定、计数和体外药敏试验。结果:1642例标本阳性率24.4%(401/1642),其中女性32.1%(358/1115),男性8.2%(43/527),阳性率女性显著高于男性(P<0.05);Uu阳性率23.50%(358/1642),M H阳性率0.12%(2/1642)和Uu+M H混合感染阳性率0.85%(14/1642)。Uu对强力霉素、交沙霉素、氧氟沙星、红霉素、四环素、环丙沙星、阿奇霉素、克拉霉素、原始霉素的耐药率依次为1.3%、0%、35.3%、3.1%、1.3%、61.8%、2.0%、3.1%、0%。结论:上海地区泌尿生殖道支原体感染率高,女性显著高于男性;9种抗生素中交沙霉素、原始霉素、强力霉素的抗菌活性高,而对氧氟沙星、环丙沙星已产生很高耐药性。更多还原

【Abstract】 Objective To investigate the mycoplasma infection and the susceptibility to drugs in patients with urogenital tract infection. Methods The detection of mycoplasma and the susceptibility test to 9 antimicrobial agents were performed by IST2 kit of BioMerieux company. Results Among the 1 642 suspected cases, 401(24.4%) were positive with mycoplasma. The positive rate in the females was significantly higher than that in the males (32.1% vs 8.2%,P<0.05), 385(23.50%)was infected with ureaplasma urealytica(Uu), 2(0.12%) with mycoplasma hominis(MH) and 14(0.85%) with Uu plus MH. The resistance rate of Uu to doxycycline, josamycin, ofloxacin, erythromycin, tetracycline, ciprofloxacin, azithromycin, clindamycin and pristinamycin was 1.3%, 0%, 35.3%, 3.1%, 1.3%,61.8%, 2.0%, 3.1% and 0%, respectively. Conclusions There is a high urogenital infection rate with mycoplasma in area of Shanghai,which is higher in the female than that in the male. The mycoplasma has become more resistant to ofloxacin and ciproxacin, but is still susceptible to other antimicrobial agents.更多还原