【摘要】 <正>在心力衰竭过程中,炎症细胞因子的表达方式与经典的神经激素(如:血管紧张素、去甲肾上腺素)相似,这些炎症细胞因子,包括:肿瘤坏死因子(tumornecrosisfactor-α,TNF-α),白介素1β(interleukin1β,IL-1β)和白介素6(IL-6)等,在心力衰竭的发病过程中发挥重要作用。了解炎症细胞因子在心力衰竭中的作用具有十分重要的临床意义,本文就这方面的研究进展进行综述。更多还原

【Abstract】 Previous reports have shown that cytokines and cytokine receptors are independent predictors of mortality in patients with advanced heart failure. Recent studies demonstrate that cytokines, such as tumor necrosis factor, interleukin 1 and inter-leukin 6, play an important role in the pathogenesis of heart dysfunction in padents with heart failure. In this review, we summarized the importance, expression and mechanism of cytokines in the development and progression of heart failure.更多还原