【摘要】 目的　检测血管活性肠肽(VIP)在寻常性银屑病皮损表皮中的水平,探讨其与银屑病发病的关系。方法　应用免疫组化法检测了VIP在24例寻常性银屑病皮损表皮中的分布。以18例正常表皮为正常对照。结果　寻常性银屑病皮损表皮中VIP的阳性检测结果明显高于对照组(P<0. 05)。结论　VIP阳性的检测结果增高可能与银屑病的发病有关。更多还原

【Abstract】 Objective To detect the vasoactive intestinal peptide(VIP) in the lesions of psoriasis vulgaris.Methods VIP in epidermis specimens from 24 patients with psoriasis vulgaris and normal epidermis from 18 healthy volunteers were examined with immunohistochemistry.Results Compared with the normal epidermis,the positive rate of VIP in epidermis of psoriasis vulgaris were significantly higher than that in normal controls( P <0.05). Conclusion The higher lever of VIP in the epidermis of patients with psoriasis vulgaris may play a partial role in the pathogenesis of psoriasis vulgaris.更多还原